PROGRAM

Thursday 28^th November 2024

Autoimmunity: from immunopathology to the bed side

 08:30 WELCOME COFFEE

9:00 INTRODUCTION

FONDATION ARTHRITIS SESSION – PhD grants

Moderators: Simon Glatigny and Patrice Decker

09:30 Norma SAAD, University Montpellier, France

Role of miRNAs in the pathophysiology of arthritis in patients with familial Mediterranean fever

10:00 Alejandro ARCO HIERVES, University Paris Saclay, France

Role of m6A methylation of RNA in salivary gland epithelial cells in Sjögren’s syndrome

10:30 COFFEE BREAK

FONDATION ARTHRITIS SESSION: EMERGENCE programs

Moderators: Jérôme Avouac and Claire Vinatier

11:00 Jérôme BITON, University Sorbonne Paris Nord, France

Involvement of SLAMF4 receptor in orchestrating the pathogenic cytotoxic immune response in rheumatoid arthritis.

11:30 Guillaume COURBON, University St Etienne, France

Fibroblast growth factor 23 production and post-translational modifications in rheumatoid arthritis: association with bone loss and iron metabolism

12:00 Maria NARANJO-GOMEZ, IRMB, Montpellier, France

Multidimensional analyses of the neutrophil immune profiling in rheumatoid arthritis patients

12:30 Marc SCHERLINGER, University Strasbourg, France

Platelet selectin promotes neutrophils immunogenic death and participates in systemic lupus pathogenesis.

13:00 LUNCH BREAK

FONDATION ARTHRITIS SESSION: focus on rheumatic diseases

Moderators: Marion Espeli and Jérémie Sellam

14:30 Ulrich MEINZER, Institut Pasteur, Paris, France

Role of the composition of peptidoglycan fractions generated in the gut and their dissemination on the development of chronic arthritis in children.

15:00 David MOULIN, University Lorraine, Nancy, Lorraine

Restoring tryptophan metabolism to treat rheumatoid arthritis.

15:30 Claire DAIEN, CHU Montpellier, France

Microbiota-gut-brain axis: prominent contributor to pain sensitization in patients with Rheumatoid Arthritis

16:00 COFFEE BREAK

PHILOSOPHY OF SCIENCE SESSION

Moderator: Florence Apparailly

16:30 Thomas PRADEU, University Bordeaux, France

Why immunologists have no other choice but to do conceptual & theoretical immunology

DISCUSSION PANEL/TABLE RONDE

Moderators: Laurène Bernard, Alexandre Maria and Yves-Marie Pers

17:00 Le regard des patients face à la recherche (in French)

AFL+ (Marianne Rivière), AFP^ric (Irène Pico-Philippe), AAI (Janig Kerouedan, Yann Cloarec), AFGS (Françoise Pellet), France Vascularites (Raphaël Darbon), Partenariat Patient Institut Imagine (Célia Cardoso)

19:00 GALA EVENING

Friday 29^th November 2024

Immunotherapies: from oncology to autoimmunity

8:30 WELCOME COFFEE

METABOLISM AND IMMUNITY SESSION in partnership with the SIRIC Montpellier Cancer

Moderators: Nathalie Bonnefoy and Laurent Le Cam

09:00 KEYNOTE Max MAZZONE, Center for Cancer Biology, Leuven, Belgium

Harnessing tumor metabolism to overcome immunosuppression

09:30 Jean-Ehrland RICCI, C3M, Nice, France

Metabolic control of anti-cancer immune responses

09:50 Emmanuel DONNADIEU, Institut Cochin, Paris, France

Enhancing CAR-T cell migration by boosting mitochondrial metabolism

10:10 Valérie DARDALHON, IGMM, Montpellier, France

Metabolic reprogramming of T cells to optimize anti-tumoral functions

10:30 Selected abstracts

10:40 COFFEE BREAK

IMMUNOTHERAPY SESSION in partnership with Fondation Arthritis: the missing link between check point inhibitors and autoimmunity

Moderators: Anne-Sophie Korganow and Florence Apparailly

11:00 KEYNOTE Andreas RADBRUCH, German Rheumatism Research Centre Berlin, Germany

Immunological memory as a roadblock to regeneration of tolerance in autoimmunity". This will include targeting of memory plasma cells

11:30 Xavier MARIETTE, Université Paris Saclay, France

Anti-inflammatory biotherapies and cancer: the in and the Yang

11:50 Patrick BLANCO, CHU de Bordeaux

Cancer-derived peptide to treat autoimmune disorders

12:10 Mark PEAKMAN, Director of auto-immunity cluster, Sanofi

Novel medicines for immune modulation

12:20 LUNCH BREAK

NEW TECHNOLOGY SESSION: therapeutic tools or biomarkers ?

Moderators: Marie Morille and Alexandre David

13:45 KEYNOTE Roy VAN DER MEEL, Eindhoven University, Netherlands

Nature-inspired nanotechnology for RNA delivery to immune cells

14:15 Philippe RONDARD

Innovative therapeutic tools for brain diseases

15:05 Martin VILLALBA

Generating CAR-like NK cells for autoimmune disease treatment

14:50 Selected abstracts

15:00 COFFEE BREAK

CAR-T versus MSC-CAR SESSION: what have we learned from cell based clinical trials?

Moderators: Farida Djouad and Guillaume Cartron

15:30 KEYNOTE Daniel OLIVE, Marseille Immunology Biocluster, France

16:00 Iain MCINNESS, University of Glasgow, UK

Deconstructing synovial immune responses

16:20 Massimo DOMINICI, Università degli Studi di Modena e Reggio Emilia, Italy

Gene modified cells to deliver deadly ligands and receptors

16:40 Karin TARTE, Rennes, France

Title

17:00 Selected abstracts

DISCUSSION PANEL

Moderators: Christian Jorgensen and Nathalie Bonnefoy

17:10 From bed to bed: how to make a link between academic research and medicine

Flash Therapeutics (Christine Duthoit), INITS (Christine Rochon), UTC Rouen (Olivier Boyer), EFS (Hélène Rouard), CHU Montpellier (Guillaume Cartron, Alexandre Maria)

FREE MANDATORY REGISTRATION

POSTER SESSION

SYMPOSIUM VENUE

ACCOMODATIONS

GALA EVENING