Risk of tumorigenicity in mesenchymal stromal cell-based therapies--bridging scientific observations and regulatory viewpoints.
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Cytotherapy, 2013, 15(7):753-9. doi: 10.1016/j.jcyt.2013.03.005
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Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue.
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Donor selection and release criteria of cellular therapy products.
Eichler H, Schrezenmeier H, Schallmoser K, Strunk D, Nystedt J, Kaartinen T, Korhonen M, Fleury-Cappellesso S, Sensebé L, Bönig H, Rebulla P, Giodano R, Lecchi L, Takanashi M, Watt SM, Austin EB,
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Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells.
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PLoS ONE, 2013, 23;8(4):e62582. doi: 10.1371/journal.pone.0062582.
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Immunological characterization of multipotent mesenchymal stromal cells--The International Society for Cellular Therapy (ISCT) working proposal.
Krampera, M., Galipeau, J., Shi, Y., Tarte, K., Sensebe, L., and MSC Committee of the International Society for Cellular Therapy (ISCT)
Cytotherapy, 2013, 15(9):1054-61. doi: 10.1016/j.jcyt.2013.02.010
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Platelet lysate coating on scaffolds directly and indirectly enhances cell migration, improving bone and blood vessel formation.
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Tissue-specific and SRSF1-dependent splicing of fibronectin, a matrix protein that controls host cell invasion.
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Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells.
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Clinical-grade mesenchymal stromal cells produced under various good manufacturing practice processes differ in their immunomodulatory properties: standardization of immune quality controls.
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Long-term detection of human adipose-derived mesenchymal stem cells after intraarticular injection in SCID mice.
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Arthritis Rheum, 2013, 65(7):1786-94. doi: 10.1002/art.37960
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Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2
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Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis
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Nicotinamide phosphoribosyltransferase/visfatin expression by inflammatory monocytes mediates arthritis pathogenesis
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GMP-compliant isolation and expansion of bone marrow-derived MSCs in the closed, automated device quantum cell expansion system
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