Toulouse platform
RESTORE institute, CNRS U-5070, EFS, ENVT, Inserm U1301
Research topics
The ECELLFRANCE Toulouse platform conducts research on the therapeutic use of bone marrow-derived mesenchymal stem cells (MSC) and adipose-derived stromal cells (ASC) in the context of cardiovascular pathologies and ischemia.
Expertise
- Characterization of MSC and ASC properties (Trophic, regenerating, angiogenic, cardiac and immunomodulatory)
- Genetic stability of MSC/ASC
- Security and efficacy tests of CSM/ASC clinical batches
- Mouse models of ischemia (leg), cardiac ischemia (implementation and follow-up of the models, cell therapy treatment)
- Translational research
Facilities
- MSC/ASC human production from different tissue sources
- Flow cytometry platform (analysis, cell sorting)
- Laboratory animal house of rodents compliant with Good Laboratory Practices ("GLP") (murine models for cardiac ischemia, leg ischemia)
- Molecular biology platform
- Histology core facility
- Proteomics platform
- Imaging platform
- Redox platform
Keywords
Mesenchymal stem cells (MSC), adipose-derived stromal cells (ASC); ischemic diseases, secretome, metabolomics.
